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DeCS
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Descriptor English:
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Neurotransmitter Uptake Inhibitors
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Descriptor Spanish:
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Inhibidores de la Captación de Neurotransmisores
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Descriptor Portuguese:
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Inibidores da Captação de Neurotransmissores
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Synonyms English:
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Inhibitors, Neurotransmitter Reuptake
Inhibitors, Neurotransmitter Uptake
Neurotransmitter Reuptake Inhibitors
Reuptake Inhibitors, Neurotransmitter
Transmitter Uptake Inhibitors, Neuronal
Uptake Inhibitors, Neurotransmitter
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Tree Number:
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D27.505.519.562.437
D27.505.519.625.600
D27.505.696.577.600
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Definition English:
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Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. |
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Indexing Annotation English:
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GEN or unspecified; prefer specific groups or specific drugs; coord IM with specific neurotransmitters /physiol (IM); DF: NEUROTRANSM UPTAKE INHIB
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History Note English:
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93; WAS TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92; NEUROTRANSMITTER UPTAKE INHIBITORS, INHIBITORS OF NEUROTRANSMITTER UPTAKE & UPTAKE INHIBITORS, NEUROTRANSMITTER were see TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92
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Allowable Qualifiers English:
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Record Number:
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30902
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Unique Identifier:
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D014179
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Occurrence in VHL:
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Similar:
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DeCS
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